About Us

Focused on Bringing New Pulmonary Medicines Forward

Who We Are

At IRulya, we are committed to transforming the lives of patients facing serious, underserved conditions by developing potentially disease-modifying therapies to treat their underlying illness. Our approach is centered on mTOR dysregulation, a biological mechanism implicated across multiple pulmonary conditions.

A Pulmonary Disease Focus

Many severe pulmonary conditions remain difficult to treat, with few—if any—treatment options that meaningfully alter the disease course. IRulya was founded to pursue an approach that directly impacts the underlying disease biology, designed to deliver such therapy directly to the site of disease in the lungs.

A Biology-Driven Approach

Our research is centered on mTOR dysregulation, a pathway that is hyperactivated and implicated in multiple pulmonary diseases.

A Therapy Designed for the Lung

Our lead investigational therapy, LAM-001, is a once-daily inhaled formulation of the mTOR inhibitor rapamycin, designed to deliver treatment directly to the lungs. We are evaluating LAM-001 in pulmonary hypertension associated with interstitial lung disease (PH-ILD), bronchiolitis obliterans syndrome post lung transplant (BOS), and sarcoidosis-associated pulmonary hypertension (SAPH).

Leadership Team

IRulya is led by an experienced team of scientists, clinicians, drug developers, and business leaders united by a shared commitment to advancing therapies for serious pulmonary diseases.

Brigette Roberts
Chief Executive Officer & Board Member
John Militello
Chief Financial Officer
Keith Fandrick
Chief Operating Officer
Joan Edwards
Chief Quality Assurance Officer
Eric Fink
Chief People Officer
Ed Parsley
Acting Chief Medical Officer
David Muccino
Sr. Medical Director
Patrick Sarmiere
Senior Vice President of Non clinical Research

Board of Directors

Brigette Roberts
Chief Executive Officer & Board Member
Drayton Wise
Board Member
Leone Patterson
Board Member
Catherine Bonuccelli
Board Member

Scientific Advisory Board

Paul Yu
Paul Yu, M.D., Ph.D.
Director, Cardiovascular Research Center at Massachusetts General Hospital. Associate Professor of Medicine, Harvard Medical School
Aaron Waxman
Aaron Waxman, M.D., Ph.D.
Director, Pulmonary Vascular Disease Program at Brigham and Women's Hospital. Associate Professor of Medicine, Harvard Medical School
Steven Nathan
Steven Nathan, M.D., F.C.C.P.
Schar Chair, Advanced Lung Disease and Lung Transplant Program, Inova Health System. Professor of Education, University of Virginia
Steve Hays
Steve Hays, M.D.
Medical Director, UCSF Advanced Lung Disease and Lung Transplant Program. Professor of Medicine, University of California, 
San Francisco
Robert Baughman
Robert Baughman, M.D.
Professor Emeritus, University of Cincinnati